- Karen Mitchell, 39, was inspired after reading plight of Alice Pyne
- Teenager lost battle with rare form of cancer in January 2013, aged 17
- Before she died she urged people to join the bone marrow register
- Ms Mitchell tweeted Alice to promise she would - and teenager was delighted
- But at 25st and with a BMI of 60, Ms Mitchell was rejected for being too fat
- Has now lost 11st 7lb and next week will donate bone marrow stem cells
A woman so inspired by the plight of a young girl dying from cancer shed 11st in order to help other people battling the disease.
Encouraged by a tweet from terminally ill Alice Pyne, Karen Mitchell created her own 'bucket list', which included losing weight and saving lives.
Pride Of Britain winner Alice, who had fought Hodgkin's lymphoma from the age of 12, took to social media to urge people to join the bone marrow register.
Karen Mitchell shed 11st 7lb after promising a dying teenager she would join the bone marrow register
After seeing it - and being deeply moved by the teenager's blog - Ms Mitchell decided she too would sign up to donate her stem cells and save lives.
But at 25st and with a BMI of 60 - well above the healthy limit of 25 - she was rejected.
Determined to fulfill her pledge, she even sent Alice a tweet, promising she would lose weight to join the register.
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