Trouble losing weight? Leptin resistance may be to blame

Dear Pharmacist: I'm frustrated and happy at the same time because last week you taught me about a blood test called leptin and how it relates to obesity. I've been the same weight for five years and can't lose anything, yet I eat very little. Please share more. -- A.S., Gainesville, Fla.

Leptin and leptin resistance may explain why you eat nothing and hold on to weight.

Leptin is your stop sign at the dinner table. This hormone is released while you're eating. Special fat cells in your body secrete leptin, which sends a message to your brain saying, "Stop eating, you're full now!"

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